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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0a0bbceff4014fce5112166f667d569f1ed6f50f0bd3f51ef5c9693fe738784' 
  AND token = '+IRh/nnDc1hXPH4nfcjIK1L8SICHOQoUG9MkLBDbxoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}