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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95f96d99844cdffa1fd34f1d5c85d8d12cdec09a45b522d419bfacef645c817f' 
  AND token = 'OW9mTy50zNEnmwMMBxTrDzODlzh3uZ1Sw/atH5x/x5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}