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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88781bf3b38a0529e70085744c5f0a3dc3208f640d66acd9cb476e3b7100a7c7' 
  AND token = 'JPmz5eGrcyplxRN8cLm1rYMN66LAKsoRisjBdoOuMVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}