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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16da66ca611d0d70ea00a3762d7e7572675d4bc47a19627062959b9bdffb95aa' 
  AND token = 'orprOO5xojE2N9E19GbVtqVlMmSOltNaTW/DXq7Erl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}