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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efe484c4be4df3664270b44edf45ae83b9fe3095e4466749d4434ba071fe9c4' 
  AND token = 'OlUnVtzHa9iKR3eSOzhQdgf+0a+yiNPkTxkXdWMp9iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}