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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b5690dcc16700f480019315501f74cedd469e2b1348a7463722db8d1a18903' 
  AND token = 'IwI42l/2HwlUIEjCFtCsS1p930P1zpw1qthV/T6Tyuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}