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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d14f36146b43537e7eb79798b6cbc4a1212e8766213107de380ac3012d718d' 
  AND token = 'j8z4HO9In998IKpR7I4KjZIkiQcxDxJ1fPhWIVU6sqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}