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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe3317b8c1f2f63366369ff9f3227a2a9dcbfa024de558d269021d5694713b5' 
  AND token = 'PZN5Bt7VK02G57qL2JAqgTC8EOA/TpsK5pD3JrigIxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}