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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da3f1607ce13043f12a8f55fb5c509068be892be7c09dfd226f8d2b8ad5b5f66' 
  AND token = 'p0dcNIBEXpp8O3LhugXtCYEiBWjZ3g5y2BvY8U4WgQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}