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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2e9c64ade365f60c82661ee8b21a8022a8aaf31fdd32abca19accfb6197c672' 
  AND token = 'fp7Viua2b99MGHfsHMNCokEb1ieSM6KIkZarSgKRtx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}