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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee791c47eb9ab2817e980e144423beaa0a9652927673252d59d7480e7cc8b94' 
  AND token = 'fgTB1ZApmqLYc7qBwLdfTfuknGMZRqJ7hc/7q/E0Eds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}