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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc47dbfeb3398c6d44e737350c4e579e2fde7a142902a9728be29039daf4cf7c' 
  AND token = '6/+k5EaixcFMu505vnkIgZJLYSqCEVqZo5ZWb6g0cj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}