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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c76a4ef9dd69208ecbf536ec098158f64ded14af196e6c49bb4d15ddad317703' 
  AND token = 'PzdJUIyjeEbAMvbSpCDMvRrqB+DDYC/9iMK5ObIGPsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}