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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18688e01d3575059628e8daa0fd9349967b22c3d19d7972dd43474eaa080d26f' 
  AND token = '9+7WOs/yv9p9TgwQ9BMDXMoT8wR/IayfQj7bfc2ne9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}