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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218c9f86370e0bb2ec19e2a3c38a035b30af32532532bfa9a613b9a4f8158f45' 
  AND token = 'uU4cY+efOe83IoUrV872n5gMAXgiCOBvP0hUCCKMMUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}