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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99d6385739040fecba2d8fa57fdce41038945a4d4823dea9f0c13f08e4cf2885' 
  AND token = 'UHIYSVVJ901h8k0jq0dwMQci817Kil4IaDtLoQhCAy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}