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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38af85e667bee378a0af14e5fc18180e49fa0a4c472bfac18378c192e9b2678' 
  AND token = 'WOT2ST198CDNuPFdr4/RCBdRJiudG5J4D3FObRH2buU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}