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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53650f3d2df285d6db529c91a403c78d0528d4d8f458950261f6b083e249edc7' 
  AND token = 'KXg5FBUhk8wwpU2QXi+BSH7hMf4hIqLPr1RQTBIkpQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}