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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a0669355ac24e93205aa416b3cb471049cbf8440b22541db30f6154f40aa97' 
  AND token = 'ANTN+QEK2D2VvtN0F6I0Xl4SqREcmIFHMdQopbvWk18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}