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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1893c20551c112f08d8e6fa497bbaf8e07c55b845b6fb14f9bc9eca25d49a380' 
  AND token = 'fQEEAggQRqx/jpPPGnwIooqj3nIc7E1ZXjsDA9m6bCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}