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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78853354ceff1f97c3f7732b4b1f28131a4eb520e64f89d5f6f0a94a7f366dc5' 
  AND token = '2NyMmTMiHUMw38XpE0AG6ABjD48W7uxctaMLgFTZr90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}