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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1881aa9f87a1a1c4d8f5c784b2f7f8bbfc3e1471a6410f0a657619db5020e8a0' 
  AND token = '0UDlKF5zIoLucbQzIz9kft7PzbpzUKQwMvbJddfl6EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}