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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b243c1fa8a0322540c1465cc7a0a651cc7fc5d29b4b40f30f469178cbdceb183' 
  AND token = 'ox2m5Brt16bW/iKY4LOZg2WoPUBffxOSaAnhXf7TuCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}