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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9f95bf292e186784df06fd9e61a05e03006d087a2638b73d3d93858b1dd5d7' 
  AND token = 'IDvst/I2mQ6rvSIuiY90dhDfpWlxx2U0pDe7w8xw3E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}