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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd72cec7ad745edb1e6effb50a36c1f6066d0bbec6e3833136930d3a099748f4' 
  AND token = 'o1Q1BO9Y5fQEtbyuxeupRTveDH3vz7fDHkMHEoROvhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}