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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ef6ccd796a886681eac1bc0bbceb3de8c4cfc0beb93e5e193b110adbc80246' 
  AND token = 'I7AarH9XmpVrKv+WtUptoI3dGg9yvY+MUwtLg0S+Wdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}