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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af78b1ddaa3034c7d779317caf3cf6b8f4420abcfb92b88d1f7130025c3ec3e4' 
  AND token = 'i3+x6ocVjA1g5TUKbJ6KqiQFbkVLar0xfW6UNm3VGAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}