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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0b99136077b67d3d116857966c834809f80836308a1a0bf5baeb7239e595a0' 
  AND token = 'FN0gGYYV5ajbwohRVWRGMBr+Z7KoJX5YEd6OltAZNaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}