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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '633fd5631cd410e41aca2f361a649a66e0ece04a927f8b01c1d664cded459d90' 
  AND token = 'J4CS2Bov9Oz9+Bev/GPrmPD4IG0w8uPNDOcuDqU+S74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}