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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce01a9a683867ce470e41f50895b4047b174d6bb8aad08d0027e3f691ad75f48' 
  AND token = 'XS9XAINZ49WfRD1X1evHCDtG7nEo1HsgMnKJZ1eMDwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}