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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72260389c7fbd9ce9b8a8dc74ad8be123be78473ae3630c3ab03ad622668b610' 
  AND token = 'C+RL1eu9HrSxK6Arr1vgYyXnBl7MdM+RElJxKY//hvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}