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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2720b8e65bea17963afdfbf557f9b43afe4b2ce7907df341fc20cf46c5257c6a' 
  AND token = 'UkRAdMQzPKes0GLv2nuhwF3GTfysIq11zR4rLeZ3oUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}