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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd642e6fdc6f26ed9fdbee9e6e8629b163ed08b24fa857103f6577a9205e8844' 
  AND token = 'zCvYvttg3WMAxUy8rDC8CzneyIdMNXwZTeP2oNvxDTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}