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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07244243994688ce79043ebf76b8a751ae9358b22845ca0bf09f55d6e2ce9f39' 
  AND token = 'NeDr+EOanSPDo1z75MF/EUcYu79KSKfWzy2Dir/MsWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}