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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b12693861c51d422c55ed07bad9a0de960c1ea82d12feca00932bc80ecc249a' 
  AND token = 'gsOUEpr9glxNDHQUSbpMY9eHhbel1tA4V7lX8ZqJRgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}