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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2679a4a98e10bd0e0c275d2397a5294c35b51b4615d837a23b208b1fb8b08b9' 
  AND token = 'CtFWDV4pUTr+1Q6mFnMxKRJaxFJRArz1C6H3WDKUPMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}