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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab1bd92f9e4d1378f822e228b54624bf6aeed0a796c4d6b82e057b4b58bbdec2' 
  AND token = 'ZVJIcL5PXAjaNi0AiiiRt2rD3hY1GtoY2NOSd2EZLFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}