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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf718ee2ef083b8b55b56e397fa6d42a70fdf6546c516684c6b18f04c9b2c7f' 
  AND token = 'cDJDeYgZQzZJXgLTQBWBTBTJf4RM2CpCiiMAcCavd74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}