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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2294006e62ea11f8051e2aad5117d8a719c38a270e576b99126aa10dc268cf35' 
  AND token = '+yaVTHqw1mLy+Nf0PWk2gJWFEj78qFSpmq3AuyYN+bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}