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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7463018ca0c12402b8939585c439afd62efd47e784a5e25a21d9f2a11f7982' 
  AND token = 'JKPiRtzxOpK7YBy6mZWlUTLhKjuUxx3TTucdEr0CbN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}