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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0da66cea368346b917bf599ac11ab2c91e256ff93c874022668104ab7eb3f29' 
  AND token = '/lWoSdNEHlhMOGnzPnSY9I3IoHq9LN7FlgXFIaffL8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}