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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5607682bf31371c9fe56c855cba3ac5b894f2612947b3e782d462df08986f9a5' 
  AND token = '89LeOhsQXMMi/x5FwLonBBv91vcajUxcF3SbKNjwHQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}