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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e004e76ff1d498f2d809e238431e03643da735d20450856ea3f15754a87bed4' 
  AND token = 'ZEKW+UO4B0gznWQSFXuIB112HlksTZAyFPXMO1WaySk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}