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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f45de641115e21848f5a623a36466533e81fc0f399a64e59178347a90326992' 
  AND token = 'W3VrA7ZwZuaJWGta64ZxYuq6gjq8PUE6Gnv7lcEReBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}