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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3807a9026cbebc2b8302e81bae88f9ce07b1e7b4e6c2819366e5abcc03bff39' 
  AND token = 'k8aVceN/S2DCKnSzEalj1aDycEAZRzcEsHKHpEulhHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}