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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b03ee569000e3840b3e768c4cb7f1e12d5f1592441feef7399af0796b976c4' 
  AND token = 'S3N5+ZPSIbSf3y8GHdMq6b0/i7owmsZUlRGZLBpxdyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}