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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e1ac4b410d81f014c1861a28402006aba226b350323b87329cd42c49750998' 
  AND token = 'EmJGf61HkB1qEG6SfjOPdLNy6cSnix+Y8wTNlKfkCQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}