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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de027a99837a33837f6e11d5e247a3a4a11c4d7713b6457f519b087964c7f9da' 
  AND token = 'xNMk5QFnJEW5UCh7KfzewvFiP+bU8+MgerrMSbdrUtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}