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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03504154a646b3c1fc04bd4a31c225cc4dc2c478dbd94838ad4e4e42ac079811' 
  AND token = 'Ywq4Rr6lhkvuxYJ3HBPW+dJWaE7CyEC9nOfRh0Rbt1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}