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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd50a7ff0b0be814ecb32cd6d78eca60a10445a7f9fb1f2d57c97fa8801c40e1b' 
  AND token = 'jO88xJQLa/cp9EHUYAMiaNoBY6SA+gewz6CjoSF1kgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}